MAME

Some MAME Variations:

MAME
MAMEUI
MAMEUIFX
MAMEUIPlus

Tested and working with light guns:

MAMEUIFX64 No Nag! Raw Inputs (v0.171) Download

MAME64 Command Line (v0.179) Download

**NEW** MAME Automatic Controller Configuration Utility:

* This is hands down the easiest way to configure every game in MAME.
* Allows you to map controllers for up to 6 players!
* Simply clicking enable, then start MAME.
* As an added bonus, you can customize controls in less than a minute.
* Much easier to use then Controller Remap and ControllerRemapGUI.
* Automatically updates when controllers are connected and disconnected.
* No more enumeration issues which cause IDs to change in MAME.
* Controllers stay mapped even after restarting your PC.
* The Advanced Tab allows mapping any controller to any type of game, or you can pick and choose!